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What does letrozole do to your body? Uses. This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.
What is the alternative to tamoxifen? Earlier ATAC results found that Arimidex was more effective than tamoxifen in reducing the risk of recurrence of early-stage, hormone-receptor-positive breast cancer in postmenopausal women. Other studies comparing tamoxifen to the other two aromatase inhibitors (Aromasin and Femara) have shown similar results.
What happens if I stop taking tamoxifen? Tamoxifen may cause hot flashes and increase the risk of blood clots and stroke. Research has shown that about 25% of women who are prescribed hormonal therapy to reduce the risk of recurrence after surgery either don't start taking the medicine or stop taking it early, in many cases because of side effects.
How much does tamoxifen reduce the risk of recurrence? Tamoxifen, also known by the brand name Nolvadex, is one of the more commonly prescribed medications used to prevent breast cancer recurrence. When used appropriately, it may reduce the risk of breast cancer coming back by roughly 50 percent.
Is there an alternative to tamoxifen? What's more, one of the aromatase inhibitors, a drug called Femara, or letrozole, has been shown to take over after five years of tamoxifen and keep the benefit going. The other two may do the same. Some doctors would now start with Arimidex or the others instead of tamoxifen.
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